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However, the previous studies could not avoid the confounding effects of the endogenous carnitine background when attempting to evaluate the effects of administering exogenous l- or d-carnitine
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One study found that use of the pramlintide/metreleptin combination resulted in 11.5 kg weight loss over 20 weeks compared with 7.4 kg and 7.9 kg weight loss respectively in participants receiving either metreleptin or pramlintide monotherapy [88]
Possible side effects include: headache, flushing (warmth or redness of the face), dizziness or light-headedness, nausea, or transient fatigue/somnolence
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