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Classic experiments performed in Baserga's laboratory have demonstrated that anchorage dependency can be acquired when the number of IGF-1Rs at the cell surface is increased to certain amount (Baserga, 1999)

For example, B12 is found in animal products, like red meat and eggs, so if you dont eat animal-based foods, then youre probably not getting enough

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It has the ability to freely penetrate the endothelial barrier and adhere to the arterial wall, which can lead to the development of atherosclerotic cardiovascular disease [46, 47]