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You can consider body composition measurement every few months if it is accessible and if the method is consistent

Pharmacological inhibition of the MVA pathway impairs Sec-tRNA biogenesis, leading to GPX4 inactivation, diminished cellular antioxidant defenses, lipid peroxide accumulation, and ultimately ferroptosis induction ( Recent studies demonstrate that the bisphosphonate alendronate synergistically enhances paclitaxel efficacy, suppresses tumor metastasis, and modifies cytotoxic mechanisms in cancer therapy

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Linagliptin (5 mg): Inhibits DPP-4 enzyme, prolonging the action of incretin hormones (e.g., GLP-1, GIP)