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You should not take semaglutide if you have 3 Personal or family history of medullary thyroid carcinoma (MTC) or other active thyroid cancer Multiple endocrine neoplasia syndrome type 2 (MEN 2) Known allergy to semaglutide or its components Compounded semaglutide is contraindicated for individuals with certain conditions, including kidney disease, an unknown cause of pancreatitis, active gallbladder disease, diabetic ketoacidosis, type 1 diabetes, pregnancy or plans to become pregnant, suicidal ideation, or diabetic retinopathy