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"Effects of DSIP in man." European Neurology

Phase 1 corresponds to a high level of activity in the primary afferent as a result of C-fiber activation due to peripheral stimulation, whereas phase 2 results from a continuous low-level small afferent input, together with a facilitated state of spinal processing [21]

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Most people report visible or physical changessuch as improved skin hydration or better joint comfortafter 8 to 12 weeks of consistent daily use