ALT elevations have been associated with asunaprevir in other combination regimens but are only rarely associated with changes in other liver function test results.19- 21 In trials of other all-oral regimens in patients with cirrhosis, high SVR rates have been achieved, although maximizing SVR rates in this population often requires extended (24 weeks) therapy and/or the inclusion of ribavirin
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The use of MRI to monitor the presence of ARIA has also been essential to monitoring safety outcomes for treatment with anti-amyloid therapies (Cummings, 2019)
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