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Other Renal disease symptoms such as kidney stones, premature arthritis, anaemia, heart disease, pancreatitis and other joint and bone involvement, including osteoporosis, may be present[4,11]

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Administration of angiogenesis-promoting peptides to such individuals could potentially result in accelerated disease progression and adverse clinical outcomes

Liu and Miao also demonstrated that the CycMSH peptide linked with Tc-99 m can target metastatic melanoma, implying that CycMSH might be used to identify metastatic melanoma [145]