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Think of free radicals like microscopic pinballs smashing around inside your skin, damaging healthy cells and causing "oxidative stress." This internal stress ruins skin tone, accelerates aging, and causes patchy discoloration

Such interactions create crosstalk between epigenetic layers: MeCP2, a methyl-DNA binding protein, can recruit histone modifiers, while histone acetylation status influences DNA methyltransferase access to chromatin 181,182

Two people who are the same chronological age may have different biological ages due to differences in genetics, lifestyle, and overall health

doi:10.1542/peds.2008-0819