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Investigating How GLP-1 May Contribute to Hair Loss Though not a direct side effect, a few mechanisms might explain how GLP-1 medications could indirectly contribute to hair loss

Rapid weight loss and nutritional stress are well-known triggers for a condition called telogen effluvium , a temporary shedding phase where more hairs than usual shift into the resting (telogen) stage and fall out Recent data suggest that people losing more than about 1520% of their body weight in a relatively short time are especially likely to report shedding, regardless of whether they used GLP-1s or more traditional diet methods In other words, for many people the issue is less Does Ozempic directly cause hair loss? and more Is the speed and style of weight loss putting my hair under stress? What the latest research says about GLP-1 Ozempic hair loss Emerging research has started to look specifically at GLP-1 medications and hair shedding: A large real-world cohort study found a higher incidence of non-scarring hair loss (including telogen effluvium) in people using GLP-1 receptor agonists compared with some other diabetes therapies, though it couldnt prove direct causation

Despite unanswered questions, health insurers should prepare for increasing interest in and demand for GLP-1s

Micronized progesterone, which more closely mirrors the molecular structure of the body's own progesterone, has largely replaced the older synthetic progestins used in the original WHI trial, and appears to offer improved tolerability and a more favorable safety profile [11,27]