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However, increasing structural and compositional complexity introduces challenges related to long-term safety evaluation, regulatory approval, and reproducible manufacturing, highlighting the need for rigorous validation frameworks [183]

While not a cure, this FDA-approved approach temporarily blocks the release of chemicals involved in pain transmission, reducing both the frequency and intensity of migraines

Hughes PE, Rex K, Caenepeel S, Yang Y, Zhang Y, Broome MA, Kha HT, Burgess TL, Amore B, Kaplan-Lefko PJ, et al

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