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10.3389/fpsyt.2020.561998 165 ZarezadehM.MahmoudinezhadM.HosseiniB.KhorraminezhadL.RazaghiM.AlvandiE.et al (2023)

Roderick JE, Hermance N, Zelic M, Simmons MJ, Polykratis A, Pasparakis M, et al

You may benefit from Melasma treatment if you have: Persistent dark patches on the face Uneven skin tone or pigmentation Hormonal pigmentation Sun-induced pigmentation Pigmentation resistant to topical creams Cosmetic concerns affecting self-confidence Melasma treatments are suitable for both men and women of various skin types , particularly individuals seeking professional pigmentation management

This decline may contribute to age-related diseases, reduced immune function, and slower recovery from cellular damage