Activated charcoal is commonly used: During occasional digestive upset, For food-related discomfort, In situations involving environmental exposures, As part of broader detox protocols
These carry no direct risk to milk supply or infant health
Thus, a number of studies have shown a positive association between plasma DPP-4 activity and BMI in non-diabetic individuals ( in vitro were found to be positively correlated with adipocyte size as well as with anthropometric parameters such as BMI, waist circumference and percent body fat ( Dpp4 expression is reported to be relatively low in mouse adipocytes and not to be markedly increased after high fat feeding ( However, there is also evidence pointing toward a hepatic origin of circulating DPP-4, and it has been suggested that the inclusion of some patients with unidentified liver disease may have contributed to the conflicting data regarding the association of plasma DPP-4 activity and T2DM
Gen Comp Endocrinol 299:113696 He Y, Yang T, Du Y, Qin L, Ma F, Wu Z, Ling H, Yang L, Wang Z, Zhou Q, Ge G, Lu Y (2020) High-fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice