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Dr Neil Nathan MD, has written an excellent book Toxic which is written in accessible language for most patients

The cardiovascular benefits have been demonstrated through blood pressure reductions and inhibition of LDL cholesterol oxidation

The total cost of care of those with obesity on GLP-1 drugs is substantially higher than the total cost of care of those who are obese who are not treated with these drugs

Recently, a mechanistic link was proposed in which patients who develop ICIs-related irAEs derive a survival benefit compared to those who do not, suggesting an overlap between toxicities and the treatment efficacy