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[DOI] [PubMed] [Google Scholar] 34.Faraonio R., Vergara P., Di Marzo D., Pierantoni M.G., Napolitano M., Russo T., Cimino F

SL played an important protective role in the early stage of acetaminophen-induced acute liver injury by decreasing the activity and expression CYP2E1, reducing the production of toxic metabolites, and alleviating liver injury (Yang et al., 2022)

The compound has been building in your system for over three months, steady-state concentration at these higher doses is fully established, and the cumulative effects are substantial

Given the small sample size and the anticipated non-normal distribution of within-patient changes in individuals with ESRD, the Wilcoxon signed-rank test was prespecified as the primary analytic approach