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In some cases, people with certain illnesses, such as Crohns disease, may experience intermittent rather than constant pain during defecation

Scand J Gastroenterol 26:1042- 1048, 1991 Iantomasi T, Marraccini P, Favilli F, Vincenzina MT, Ferretti P, Tonelli F: Glutathione metabolism In Crohn's disease

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