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Patients who come in with brain fog, memory issues, anxiety, or depression often experience dramatic improvements when we address their underlying gut dysfunction

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This suggestion was supported by the decrease in TAp73 in p53 wt,mut melanoma cells in the absence of any effect on p53 null cells that were devoid of Np73 (Figure 8), and the observation that TAp73 appeared to promote its own turnover as well as that of other p73 forms, including the Np73 in a transactivation-dependent manner

Following this, the animals are allowed to explore all three arms, including the previously inaccessible arm, during a 5-min testing session