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The role of ROS in the occurrence and development of breast cancer The occurrence of breast cancer, the most common malignancy in females worldwide, is generally believed to be significantly associated with the accumulation of genetic damage caused by genetic alterations, which cause uncontrolled cell proliferation and/or abnormal programmed cell death, or apoptosis [60]

however, the CNS is the primary system in which pyritinol exhibits observable pharmacological effects

Tucotuzumab celmoleukin (EMD 273066 or huKS-IL2) is an immunocytokine consisting of tucotuzumab (anti-EpCAM antibody) and IL-2 (celmoleukin) [199]