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Alternatively, as Lp glu is an intermediate formed by the OADHc that converts 2-oxoadipate to glutaryl-CoA, persistent glutarylation of the OGDHc-E2 would prevent the formation of glutaryl-CoA by the OADHc, and also render the OGDHc inactive

At the same time, it may help defend brain cells against damage from oxidative stress, which tends to build up over time

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