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The cumulative fractional labeling from palmitate and glucose in DKO cell histone acetylation matches that by WT and ACSS2 KO cells, while ACLY KO cells have much lower cumulative labeling from these two sources, consistent with unlabeled acetate feeding the acetyl-CoA pool only in those cells (Supplemental Figure 5D)

This approval validated MT-1's safety and efficacy for photoprotection

This outcome requires follow-up before any conclusions can be drawn with respect to utilization of TB-500 or related compounds in settings of cell therapy for tissue repair [8]

5, Ousia applied for a sterile compounding license in March 2024, but it was never granted