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Trials using around 1,200mg/day in divided doses showed modest but consistent improvements in memory and executive function among patients with mild cognitive impairment, Alzheimers, or post-stroke deficits.32 Some reviews also note benefits for mood symptoms (apathy, anxiety) alongside cognition.32 For healthy individuals, the benefits are more nuanced

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A 2012 study published in Journal of Pharmacology and Experimental Therapeutics demonstrated that a seven-day dihexa dosing protocol produced cognitive improvements in rodent models that persisted for at least 30 days post-treatment, despite the compound being undetectable in plasma within 12 hours of the final dose