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The patients entered into the trial had to meet the following inclusion criteria: - erectile dysfunction secondary to radical retropubic prostatectomy, with or without bilateral sparing of the neurovascular bundles, in patients in whom the prostatectomy had been performed at least 6 months but less than 2 years prior to entry into the clinical trial

Therapeutic development could involve creating small molecule inhibitors or activators of CHAC1, depending on the context

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Notably, both 16S rRNA sequencing and metabolomic functional enrichment analyses identified lipid metabolism as a target of LW