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Regular monitoring of renal function is advisable in patients with pre-existing kidney disease, as gastrointestinal adverse effects may lead to dehydration and acute kidney injury

While danuglipron has shown good efficacy in a twice-daily formulation in phase 2b testing, we believe a once-daily formulation has the potential to have a competitive profile in the oral GLP-1 space, he said

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Pharmacy and prescription drug spending plus inflation across all healthcare sectors, from hospital stays to cancer treatment, are the biggest drivers of the 7.8% expected increase in spending, according to the nonprofit organization representing large employers, which has studied healthcare costs for about 50 years