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2a, 2b)

Wang Y, Ausman LM, Greenberg AS, Russell RM, Wang XD (2009) Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats

Temperature excursions above 8C cause irreversible degradation: a study published in the Journal of Pharmaceutical Sciences found that methylcobalamin stored at 25C (room temperature) lost 30% of its potency within seven days, compared to less than 5% loss when stored at 4C over the same period