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Pseudomonas can produce lipopolysaccharide (LPS) and peptidoglycan (PGN), which act on Toll-like receptor 4 (TLR4) and NOD-like receptors (NLRs), thereby activating host immune responses ( Pseudomonas was significantly negatively correlated with biotin (vitamin B7) levels ( In addition to baseline dysbiosis, disease stage and treatment status also influence gut microbiota taxonomic composition

Specifically, egg whites, wheat protein, fish, and casein (dairy) cause the release of GLP-1.[ref] Include fiber : Fermentable fiber in the large intestines promotes the formation of short-chain fatty acids from the gut bacteria

Collectively, these studies position the System Xc /GSHGPX4 axis as a critical therapeutic node in renal I/R injury: interventions targeting pathway-related genes or enhancing key protein levels boost renal antioxidant capacity, offering novel strategies to mitigate I/R-induced kidney damage

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