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CXCL10 is the primary factor for impaired ovarian function upon NRTP The distinct effects of WCV and PD-1 immunotherapies on ovaries under NRTP provided a better opportunity for us to discover the key factor through which mouse fibrosarcoma damages ovaries

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Pre-treatment Screening : Before prescribing oxidising medications like rasburicase or dapsone, guidelines mandate testing to prevent precipitating a crisis

Effective dose range: Animal studies and early human trials generally use subcutaneous doses ranging from 0.5 mg to 2 mg per administration , depending on sex, body weight, and study objectives