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Regarding respiratory outcomes, while most findings were not statistically significant, GLP-1 RAs were associated with benefits in specific clinical scenarios, such as reducing the risk of pneumonia and improving outcomes in individuals with COVID-19, possibly mediated by anti-inflammatory mechanisms

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Zepbound was approved by the FDA in November for chronic weight management in adults with obesity or overweight with at least one weight-related condition, such as high cholesterol, high blood pressure, or type 2 diabetes

Neither study clearly answers the question of whether GLP-1 receptor agonists worsen symptoms among patients with preexisting mental health problems such as moderate or severe depression, they wrote