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Its fundamental pharmacological mode of action hinges on selective NNMT suppression: blocking excessive nicotinamide methylation reactions to elevate endogenous intracellular nicotinamide reserves, further accelerating downstream NAD+ biosynthesis

Liu J., Zhang X., Cong Z., Chen Z., Yang H., Chen G., Nanoscale , 2013 , 5 , 1810

Based on these findings, Novo Nordisk decided to study liraglutide not only as a diabetes drug but also as a potential treatment for obesity

W badaniach klinicznych czsto cikiej hipoglikemii przy stosowaniu agonistw GLP-1 bya zbliona do placebo (GLP-1 receptor agonists: an updated review of head-to-head clinical studies PMC) (Glucagon-Like Peptide-1 Receptor Agonists StatPearls NCBI Bookshelf)