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Abstract Glioblastoma (GBM) is a highly lethal disease with limited treatment options due to its infiltrative nature and the lack of efficient therapy able to cross the protective blood-brain barrier (BBB)

Patients might lack vitamins and minerals like vitamin B12, iron, calcium, and vitamin D

(2017) MicroRNA-22 suppresses the growth, migration and invasion of colorectal cancer cells through a Sp1 negative feedback loop, Oncotarget , 8 , 36266-36278, doi: Dhar, S., Kumar, A., Gomez, C

Chronic sun exposure history: Skin with a longer history of significant UV exposure often has more entrenched pigmentation patterns, which can mean a longer visible timeline even with excellent internal supplementation