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however, current evidence remains limited, heterogeneous, and derived largely from secondary analyses or observational studies rather than dedicated randomized heart failure trials

0.16 ng/ml/12 ml/day till the sacrifice) and intragastrically after cuprizone instilations, while controls received simultaneously drinking water only (12 ml/day) as well as an equivolume of saline (5 ml/kg) intragastrically after cuprizone instillations

Ozempic's once-weekly injection schedule, its demonstrated 1.5-1.8% HbA1c reduction, and the SUSTAIN cardiovascular outcomes trial data showing 26% reduction in major cardiovascular events in T2DM patients with established cardiovascular disease collectively built a clinical case that endocrinologists and cardiologists find compelling for guideline-aligned prescribing