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Tirzepatide reduced albuminuria compared with placebo, with a significant effect at 24 weeks, preceding the improvement in eGFR, which is also consistent with a decrease in glomerular hypertension as a key mechanism

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For example, diabetes GLP-1 users were more likely to be older, with no kids, and lower household incomes (less than $50K), compared to those taking the drug for weight loss, who were more likely to be younger with children and higher household incomes ($150K+)

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