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Food and Drug Administration (FDA) has not approved microdosing semaglutide, and there is no clinical data supporting its safety or effectiveness

DSIP is supplied strictly for laboratory research purposes only and is not approved by the FDA or any regulatory authority for human use, veterinary use, clinical administration, therapeutic applications, or diagnostic procedures

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The unstable psychological structure of an obese individual, oppressed by the goal of loosing weight "at all costs", entails, given the intake of these substances with addictive properties, an increased risk of breaking the psychological balance, which can hesitate in behavioral disorders that are not always reversible [105]