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Physical examination revealed bilateral pitting pedal edema (2+), bilateral lung crepitations in the infrascapular region, and underdeveloped gonads (Tanner stage I)

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Studies have shown that DFO (100 M) can inhibit ROS accumulation and cell death induced by the ferroptosis inducer erastin (225)

In Conclusion and Future Directions, we reviewed clinical and preclinical data on therapeutic techniques aimed at TMAO, with the objective of elucidating the possible prospects of TMAO-targeted interventions in disease therapy