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Pigmentation lightening for melanin-based dark circles requires 8-12 weeks minimum as brightening peptides and niacinamide gradually inhibit melanin production and promote hyperpigmented cell turnover

A biofilm was overlaid on an agarose gel to simulate the barriers of chronic wounds and the punctures of the barriers by the MNs were evaluated

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The data showed that the same concentration of LCS3 mentioned above did not affect the activity of TXNRD1 in VRK2-KO cells, but a higher concentration of LCS3 was required to induce a decline in the activity of TXNRD1 (Fig