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In mouse models of cecal ligation and puncture (CLP)-induced sepsis, plasma-derived EVs affected RBC deformability, increasing RBC rigidity [387]

351 Traditional Chinese medicines (TCMs) in preventing acute altitude illness Two trials suggested Ginkgo biloba may prevent AMS, 385,386 but others reported negative results, 387,388 potentially due to product variability

xCT inhibitors can also have therapeutic benefits for ovarian cancer cells growing in a high-glucose tumor environment (e.g., ovarian cancer cells overexpressing SLC7A11, GLUT1, PDK, glutaminase, and GPX)