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Moreover, GLP-1RA limits the inflammation induced by nuclear factor kappa, thereby reducing the expression of proinflammatory mediators like tumor necrosis factor (TNF), C-C motif ligand 2, and IL-6[12]

The good news: GLP-1 medications make this substitution significantly easier by reducing cravings for high-sugar, high-carb foods

The improved survival of animals with LPS-induced endotoxemia by treatment with GLP-1 analogs (7) or endotoxin-challenged DPP-4 knockout rats (61) is associated with reduced vascular inflammation/dysfunction

Researchers said this could open up another means of helping people battle alcoholism, but larger clinical trials are needed to confirm this