First, it directly addresses the root cause of mast cell hyper-reactivity: intracellular oxidative stress
5 Chinese Name Precautions Restricted to liver failure7 Abbreviation GSH CAS number 70-18-87 Basic Composition cysteine, glycine, glutamic acid PubChem 745-1248867 Main Functions Antioxidant, chelating and detoxifying, skin whitening, spot reduction Chemical formula C10H17N3O6S7 Storage Method Cool, dry place Molar mass 307.325g/mol7 Included in Medical Insurance Yes Melting point 189 to 193 C7 Dosage Form Oral conventional-release dosage form7 Solubility Soluble in water, insoluble in methanol, ether7 Drug Type Liver therapeutic agent, Anti-fatty liver drug7 Content Distribution Glutathione is widely distributed in nature
Collectively, the non-canonical peptide sequences, i.e., not templated in the genome, resulting from these processes will be referred to as alternative antigens (also termed neo-antigens in the literature)
Intrigued, I started researching