Other natural interventions that may benefit migraines sufferers include ginkgo biloba , lipoic acid , vitamin B6 , and ginger
It is not FDA-approved for treating any condition
No evidence package for common commercial routes FDAs briefing found no adequate human studies for the commonly proposed oral, subcutaneous, nasal, or transdermal routes
Notably, animal models have demonstrated that transferring dysbiotic microbiota from CFS/ME patients to germ-free mice can induce fatigue-like behaviors, supporting a causal role for the microbiome in disease pathogenesis ( 3.5.4 Gut microbiota-based therapeutic interventions 3.5.4.1 Probiotics Given these findings, probiotic supplementation, particularly with strains of Lactobacillus and Bifidobacterium , has shown potential to restore microbial balance, enhance SCFA production, and reduce inflammation in CFS/ME patients (Skjevling et al., 2024)