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Blanes-Mira, C., Clemente, J., Jodas, G., Gil, A., Fernndez-Ballester, G., Ponsati, B., Gutierrez, L., Prez-Pay, E., & Ferrer-Montiel, A

After first reconstitution (puncturing the rubber stopper with a sterile needle to introduce bacteriostatic water), the vial's internal environment is exposed, though the rubber stopper reseals when the needle is removed