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As previously described (Koeth et al., 2013), production of both d3-TMA and d3-TMAO were also significantly induced in the L -carnitine supplemented mice, and plasma concentrations of d3-carnitine were significantly lower (consistent with a large portion of dietary L -carnitine being catabolized at greater efficiency by gut microbes following the chronic dietary exposure) (Figure 5A)

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Metallic or altered taste sensations are occasionally reported, though less commonly than food aversions

The findings were based on a review conducted by the Food and Drug Administration using data from the FDA Adverse Event Reporting System (FAERS)