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TB-500 is currently understood by FDA and WADA research as the N-terminally acetylated seven-residue thymosin beta-4 fragment Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln

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Note: -mercaptoethanol, dithiothreitol and cysteine are known to interfere in this assay

Furthermore, genome-wide CRISPR screening identified SEC24 homolog B (SEC24B) as a key regulator of ferroptosis, and its knockout significantly inhibited ferroptosis in microglia (Ryan et al., 2023b)