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In SOD1 mouse models, end-stage disease is associated with higher markers of M1 activation (such as NOX2 and other reactive oxidative species) compared with higher levels of M2 activation (such as CD163 and brain-derived neurotrophic factor (BDNF)) at disease onset [242]

Daver NG, Assi R, Kantarjian HM, Cortes JE, Ravandi F, Konopleva MY, Kadia TM, Borthakur G, Jabbour EJ, DiNardo CD, Velasquez M, Kelly M, Ning J, Nogueras Gonzlez GM, Pierce SA, Gombos D, Estrov ZE, Kornblau SM, Zhang W, Andreeff M

Association between clinical complete response and pathological complete response after preoperative chemoradiation in patients with gastroesophageal cancer: analysis in a large cohort