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One of the important cases of RBCs oxidative stress is the intake of xenobiotics, particularly cytostatics and other antitumor drugs 17,18 , which leads to anemia, one of the most frequent side effects of cancer chemotherapy

La disponibilidad de suficientes cantidades de carnitina en el citoplasma, permite a la enzima carnitina aciltransferasa, formar acetil-carnitina, y liberar la CoA para evitar la acumulacin de Acetil CoA y favorecer la accin de la PDH

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The upregulation of NRF2 and SOD1, along with the activation of ROS scavenging pathways, can lead to resistance to chemotherapy or targeted therapy in various tumors