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Post-Reconstitution Handling: Store reconstituted solution at 28C Use within a short, validated timeframe based on experimental requirements For extended storage, aliquot and store at -20C or below Avoid repeated freeze-thaw cycles Pre-Reconstitution Storage: Store lyophilized product at 28C (short-term) For long-term storage, maintain at -20C or below Protect from light, heat, and moisture Handling Precautions: Use appropriate aseptic laboratory techniques Allow vial to reach room temperature before opening to prevent condensation Ensure solutions are clear and free of particulates prior to use Dispose of materials in accordance with laboratory safety protocols Research Protocols and Dosing Considerations Research involving L-Glutathione (GSH) varies widely depending on experimental model, cell type, and study objectives

Discarding the upper plasma, wash with treble volume of PBS for 3 times (mix blood cell with PBS centrifuge at 600 g for 10 minutes), add equal volume of Reagent I

As CIBB is designed on the basis of the CXC10 regions that bind to IL18R1 with high affinity, CIBB blocks only the binding of CXCL10 to IL18R1 without affecting the positive role of CXCL10 in suppressing tumor growth

Understanding these aspects is paramount to a successful treatment experience