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Histamine-related symptoms can overlap with food allergy, chronic urticaria, mast-cell disorders, medication reactions, migraine, dysautonomia and gastrointestinal disease

Based on this evidence, it can be concluded without any reasonable doubt that oxidative stress puts some babies and children at risk of paracetamol-induced neurodevelopmental injury, and that postnatal exposure to paracetamol in those susceptible babies and children is responsible for many if not most cases of ASD. Sil A, Ravi MD, Patnaik BN, et al

Also, human trials targeting neuropathic pain are absent

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