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Next, we used CRISPR-Cas9 to mutate two bases in the putative TFAP2 binding motif of the glp-1::v5 promoter ( glp-1prom(aa) ) that are predicted to disrupt TFAP2 binding (Fig

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CMSs CGT Access Model (Box 3) is designed to help improve access to new sickle cell gene therapies for Medicaid enrollees and reduce costs for state Medicaid programs

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