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For individuals not seeing expected results alongside managing side effects, exploring reasons for lack of progress can identify protocol adjustments that improve both outcomes and tolerability

Studies report improved sensitivity for detecting small endometriomas and assessing disease extent

Moreover, Akt1-/- mice have been shown to be protected from hypoxia and TGF--induced lung fibrosis, while Akt-overexpressing mice exhibit pulmonary vascular fibrosis (34)

call 999 if accompanied by severe systemic illness) Signs of gallbladder disease : Right upper quadrant pain, jaundice, fever (contact GP urgently or NHS 111) Symptoms of thyroid tumours : Neck lump, hoarseness, difficulty swallowing (rare, but GLP-1 agonists carry a theoretical risk based on animal studies) [15] [21] Allergic reactions : Rash, swelling, difficulty breathing (call 999 for severe reactions with breathing difficulties) Acute kidney injury : Reduced urine output, swelling, confusion (contact GP urgently or NHS 111