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Advances in siRNA therapeutics and synergistic effect on siRNA activity using emerging dual ribose modifications

Stomach acid and digestive enzymes can break down the fragile tripeptide structure before it ever reaches the small intestine for absorption

Their core value is concentrated in three key directions, as follows: i) Deep learning, network-based machine learning and other algorithms are utilized to mine patient-specific autophagy-ferroptosis molecular signatures, enabling precise stratification of treatment responders and non-responders, and providing a basis for individualized therapeutic target selection (153)

FEBS Lett 2005