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Adding to the statement, adding electron donating groups (n-butyl, methoxy, etc.) at the benzene ring was found to decrease the potency of DPP-4 inhibitors, whereas substituting electron donating group (EDG) with electron withdrawing groups (EWG) like: bromo, and nitro) tended to enhance the activity, comparing the potency of the compounds within halogen substituting (Bromo to chloro or CF 3 ) displays to see a reduction in inhibitory potency [58] (Figure 10 C,D)
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Lyssenko V., Groop L., Prasad R.B
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As more patients come forward with similar complaints, the number of lawsuits is expected to rise, creating growing pressure on the manufacturers to address the risks associated with their products
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