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Moreover, whereas its mRNA levels rapidly rise in WT mice after APAP injection, in LivPGC-1 we detected just a feeble increase of Gcl-c, probably not sufficient to enrich the GSH supply useful to limit APAP damage

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149 PentikinenV.ErkkilaK.SuomalainenL.ParvinenM.DunkelL

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Additionally, as described in more detail later in this final rule with comment period, we are delaying enforcement of these new requirements to April 1, 2026 to allow hospitals additional time to implement the requirements

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