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The most common issues are mild redness or slight swelling at the injection site, which typically resolves quickly

Prediction of pI and net charge The EMBOSS iep software (EMBOSS) ( was used to calculate the theoretical pI and net charge at different pH values of unfused albumin variants and GLP-1 albumin fusions

An updated Cochrane review in 2019 of four studies with 907 participants was very uncertain as to if ALC caused a pain reduction after 6 to 12 months of treatment